Technology Overview

The Tet Technology provides efficient, precise and reversible control over timing and level of gene expression in eukaryotic cells.
Its unusual specificity and the well studied chemical and physiological properties of the inducing agents have made the Tet System the most widely applied inducible gene expression system as demonstrated by the extensive literature available. It has been successfully applied not only in numerous tissue culture systems but also in various organisms such as yeasts, protozoans, insects, amphibia, plants and mammals, particularly in the mouse. Therefore, beside facilitating physiological studies at the cellular level, the Tet System also permits detailed analyses of complex biological processes like behaviour, development and disease.
The components of the Tet System are available through authorized reagent distributors. Commercial users can access the Tet Technology through our licensing program.